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DeCS
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Descriptor English:
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Receptor, Insulin
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Descriptor Spanish:
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Receptor de Insulina
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Descriptor Portuguese:
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Receptor de Insulina
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Synonyms English:
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Insulin Receptor alpha Chain
Insulin Receptor beta Chain
Insulin-Dependent Tyrosine Protein Kinase
Receptors, Insulin
Insulin Receptor Protein Tyrosine Kinase
Insulin Receptors
Insulin Receptor Protein-Tyrosine Kinase
Insulin Receptor
Insulin Receptor alpha Subunit
Insulin Receptor beta Subunit
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Tree Number:
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D08.811.913.696.620.682.725.400.200
D12.776.543.750.630.484
D12.776.543.750.750.580.300
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Definition English:
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A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE. |
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See Related English:
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Donohue Syndrome
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History Note English:
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2000(1977); for INSULIN RECEPTOR PROTEIN-TYROSINE KINASE use RECEPTOR, INSULIN (NM) 1983-1993
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Allowable Qualifiers English:
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Record Number:
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22649
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Unique Identifier:
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D011972
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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